Wednesday, July 23, 2014

Liposomes have numerous uses as biochemical and biophysical tools: as vehicles for the delivery of both water and of oil-soluble materials to the cell; as immunological adjuvants; as substrates for the study of membrane properties such as rotational or translational diffusion in the plane of the membrane; and as intermediates in the construction of bilayers large enough for the study of electrical properties of membranes.

Medical Applications of Liposomes

by Liposomes on July 23, 2014

Liposomes Lipid Vesicles Liposome Formulations 122 150x150

The development of liposomes as a drug delivery system has fluctuated since its introduction in the late 1960's by A.D. Bangham. While academic research of liposomes as a model membrane system has always flourished, as the exponential growth of papers can testify, the application of these findings to medically useful products has gone through several crises. Following the original optimism in the 70's and early 80's, a period of severe skepticism ensued at the end of the 80's and beginning of the 90's, culminating in a moderate but real optimism in the mid 90's, as a result of a successful launch of the first products in the US and Europe.

In this collection of papers, the editors have gathered the most promising ideas, approaches, applications and commercial developments, thereby presenting an up-to-date compilation of the present status of the field. This includes such broad areas as anti-cancer chemotherapy immune stimulation and infectious diseases. Currently, the major areas of progress are in delivery of anti-fungal agents by conventional liposomes or lipid-based carriers and systemic anticancer therapy using long-circulating liposomes. The future applications as characterized by the direction of present day research is in specific targeting and delivery of informational molecules such as DNA plasmids (genes), antisense oligonucleotides or ribozymes. Other future developments may be in topical delivery, vaccination and in diagnostics.

Features of this book:

• Contributions from almost all the leading labs in the field

• Up-to-date, critical reviews bridged by editors' introductions

• Organized into a logical framework.

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Celsion Gets $1 Mn Career Development Award Grant From NIH for Glioblastoma ... pharmabiz.com

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Celsion gets $1 mn career development award grant from NIH for glioblastoma ...pharmabiz.comThe grant will support preclinical studies evaluating ThermoDox, the company's heat-activated liposomal encapsulation of doxorubicin, in combination with High Intensity Focused Ultrasound (HIFU), for the treatment of brain tumours. The grant, titled& ...Celsion Corporation Announces $1 Million NIH, NIBIB - Career Development ...Wall [...]

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BioPath Holdings' Liposomal Delivery Technology Achieves Major Milestone in ... DailyFinance

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Bio-Path Holdings' Liposomal Delivery Technology Achieves Major Milestone in ...DailyFinanceHOUSTON--(BUSINESS WIRE)-- Bio-Path Holdings, Inc. (OTCQX: BPTH) ("Bio-Path"), a biotechnology company developing a liposomal delivery technology for nucleic acid cancer drugs, today announced that a scientific assay has confirmed that its lead& ... Read the full story: Bio-Path Holdings' Liposomal Delivery Technology Achieves Major Milestone in [...]

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Stem Cell Options for Skin Care Burgeon as Trend Hits Big CosmeticsDesign.com USA

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Stem cell options for skin care burgeon as trend hits bigCosmeticsDesign.com USAThis synthetic ingredient named SH-polypeptide-7 is encapsulated by a liposome and targets hair bulge stem cells at the receptor sites to regenerate the skin. Coming at the problem from different paths and sources, epidermal growth factors, ... and more& » Read the full story: [...]

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Fungisome Amphotericin B Manufacturer

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Health care is one of the most important issues these days. Everyone wants a good health this time. About their health every body is serious now a day.we knows very well that Health is Wealth. If we lost our health we lost every thing. Good health and fitness has become top level priority for people [...]

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Liposomal Technology -

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Empirical Labs liposomal carrier technology under the microscope vs. other mfg. Tags: carrier, Empirical, carrier technology, microscope, Technology

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Casey Analyst Forecasts Explosive Biotech Growth Trefis

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Casey Analyst Forecasts Explosive Biotech GrowthTrefisOn the other side is a much smaller and lesser-known company with an FDA decision pending on a liposome-wrapped chemo that will advance the treatment of large solid tumors in much the same way. It is a much simpler mechanism of action. Read the full story: Casey Analyst Forecasts Explosive [...]

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Liposomes and Their Uses in Biology and Medicine

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Tags: Biomedical engineering, University of Arizona

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EDAP and Collaboration Partners Awarded EUR 1.1 Million European Grant for ... IEWY News

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EDAP and Collaboration Partners Awarded EUR 1.1 Million European Grant for ...IEWY NewsThe prototype nanocarrier is a sonosensitive liposome containing a cancer drug currently in use for treatment of breast cancer and the liposome will allow encapsulation of other type of drugs addressing a variety of pathologies. ... Read the full story: EDAP and Collaboration [...]

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