Sunday, February 5, 2012



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European Orphan Drug Status for Celator Pharma's CPX351 to Treat AML pharmabiz.com

by Liposomes

European orphan drug status for Celator Pharma's CPX-351 to treat AMLpharmabiz.comThe European Commission (EC) has granted orphan drug status to CPX-351, the Celator Pharmaceuticals' proprietary "liposomal combination of cytarabine and daunorubicin," for acute myeloid leukaemia (AML) treatment. The designation follows a positive ...Celator Pharmaceuticals Receives EMA Orphan Drug Status for CPX-351 in Acute ...FierceBiotechEC grants [...]

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Example 1 Development of 'Expansile' Nanoparticles for Drug Delivery AZoNano.com

by Liposomes

AZoNano.com Example 1: Development of 'Expansile' Nanoparticles for Drug DeliveryAZoNano.comIt is important to precisely characterize liposome size since the development of effective drugs requires that homogenous liposome particle sizes are created, which are stable and retain their drug payload. Also the detection of modifications on the ... and more& » Read the full story: Example [...]

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A Review on Topical Ophthalmic Drug Delivery Systems

by Liposomes

1K.S.Rathore*, 2R.K.Nema, 3S.S.Sisodia, 3M.S.Ranawat 1B. N. Girls College of Pharmacy, Udaipur 2Rishiraj College of Pharmacy, Indore 3B.N. College of Pharmacy, Udaipur Eye is unique and very precious organ. It is considered as window of the soul. We can enjoy and viewed the whole world only with this organ. There are many eye ailments which affect [...]

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ETHOSOMES a POTENTIAL CARRIES for TRANSDERMAL DRUG DELIVERY

by Liposomes

The literature is abounding with attempts made to enhance the delivery of drugs into the deep layers of the skin and through the skin.  Ethosomes are noninvasive delivery carriers that enable drugs to reach the deep skin layers and/or the systemic circulation. Although ethosomal systems are conceptually sophisticated, they are characterized by simplicity in their [...]

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Lipospheres in Drug Targets and Delivery: Approaches, Methods,

by Liposomes

Lipospheres in Drug Targets and Delivery: Approaches, Methods, and Applications presents an overview of the most recent applications of lipospheres primarily in the field of medicine, pharmaceutics and biotechnology. Included are chapters on preparation, characterization, delivery (of peptides, proteins, vaccines, nucleic acids) therapeutic applications to different systems and suggestions for further research. Including numerous illustrations, [...]

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Porous Nanoparticles Deliver Drug Cocktails to Tumors Nanowerk LLC

by Liposomes

Porous nanoparticles deliver drug cocktails to tumorsNanowerk LLCThis strategy relies on using silica nanoparticles honeycombed with cavities that can store large amounts and varieties of drugs loaded inside a lipid-based nanoparticle known as a liposome. "The enormous capacity of the nanoporous core, with its high ... Read the full story: Porous nanoparticles deliver drug cocktails [...]

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Synthetic Surfactant Vesicles: Niosomes and Other

by Liposomes

The self-assembly of synthetic surfactants and other non-phospholipids into vesicles was first studied in the 1970s by cosmetic scientists when non-ionic surfactant vesicles or niosomes were reported. Since this time a large body of research has sought to define these systems primarily as drug carriers and also as features of interest to the colloid scientist. [...]

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Liposome Drug Delivery Systems

by Liposomes

Guide to current liposome drug delivery technology. Applications, preparation, pharmacokinetics, stability, passive and active targeting, and industrial production. Special emphasis on "stealth" liposomes (liposomes with extended circulation times). Tags: stealth liposomes, drug delivery technology, DRUG stealth liposome, stealth liposomes

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Controlled Release of Drugs From Liposomes Using Ultrasound

by Liposomes

Liposomes, vesicles with one or more lipid bilayers entrapping an inner aqueous core, are widely used as drug delivery systems. When liposomes are smaller than 100 nanometers (nano liposomes) they have a unique capability of selectively accumulating in tumors and inflamed tissues. This phenomenon, known as the enhanced permeability and retention (EPR) effect, is related [...]

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Philips Localized Drug Delivery Development - Sonodrugs

by Liposomes

Philips is leading a major new European project to develop drug delivery technologies that could significantly impact the treatment of cancer and cardiovascular disease. By allowing drugs to be delivered to disease sites via the patients bloodstream and then activated by focused ultrasound pulses, the SonoDrugs project aims to maximize the therapeutic efficiency and minimize [...]

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